NITBIOSAFE, in vitro & in vivo characterization of nanomaterials

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nitbiosafe

¿What is nitbiosafe ?

 

nanoimmunotech  offers you a complete portfolio of physico-chemical and biological characterization services called nitbiosafe, that alllows you to perform a full set of in vitro and in vivo assays to check the risk of your nanomaterials: toxicity, biocompatibility (hemo and cytocompatibility), biodistribution, immunogenicity, sterility, among other assays.

nitbiosafe, services are based on standardized protocols and experimental environments that ensure optimal laboratory results, implementing USA recommendations and all EU regulation regarding nanosafety.

nanoimmunotech  team has been involved in the field of Nanotoxicity, being members of different workgroups and platforms, as European Platform of Nanomedicine (ETPN), having participated in several projects and networks related to nanosafety and collaborated with other partners in this field.

nanoimmunotech 
also accounts with an animal facility that allows the use of animal models for in vivo confirmation of nanotoxicity and immunogenicity, offering you the ultimate biological characterization assays for your products.


BIOLOGICAL CHARACTERIZATION SERVICES

 
 IN VITRO BIOLOGICAL CHARACTERIZATION IN VIVO BIOLOGICAL CHARACTERIZATION 
Aggregation analysis and colloidal stability Letal Dhose DL50
Nonspecific TDAR (T cell dependent antibody response)
Sterility Biodistribution and pharmacokinetics
Targeting  
Phagocytosis assay
Oxidate Stress Study: determination of the production of reactive
oxygen species
Cytotoxicity analysis of two methodologies (MTT & QUICK CELL)
Inflammation Study: production of cytokines
Complement activation test
Hematological study

PHYSICO-CHEMICAL CHARACTERIZATION SERVICES

Techniques PhysicoChemical Characterization
TEM-EDX / SEM Size, Shape, Monodispersity and Composition
Analysis of elements Content analysis of C, N, H and S
Nuclear magnetic resonance spectroscopy (NMR) Characterization of the protective organic monolayer structure of core-shell nanoparticles
Inductively coupled plasma (ICP) Identification and quantification of the chemical elements present in nanostructures
Zeta Potential Measure the Zeta Potential charge of nanoparticles
Dynamic light scattering (DLS) Hydrodynamic radius and size distribution of nanoparticles in solution
Fourier transform infrared spectrophotometry (FTIR) Characterization of the major functional groups present on the surface of the nanostructures
X-ray photoelectron spectroscopy (XPS) Assessing the nature and chemical state of the surface atoms of the nanostructures to depth of 5 nm (4-20 atomic layers)
Fluorescence spectrophotometry Analysis of fluorescent nanostructures
SQUID Magnetic properties of nanostructures
UV-visible spectroscopy Characterization of surface plasmon of noble metal nanoparticles

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CONTACT DETAILS

T (+34) 976 369 300
Email: info(@)nanoimmunotech.es
Skype: nanoimmunotech
Where we are? 

With the collaboration of:

colaboradores 2016

        

 
 
 

LOCATIONS

HEADQUARTERS IN VIGO
Edificio CITEXVI
Fonte das Abelleiras s/n
Campus Universitario de Vigo
36310 Vigo, Pontevedra, Spain

HEADQUARTERS IN ZARAGOZA
Fernando de Antequera, 2 Local D
50006 Zaragoza, Spain

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